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USA 111 , 62036208 (2014)

Glutathione-bound Mercury(II) triggers the catalytic depletion of the cellular GSH pool by a catalytic mechanism, which involves the presence of Mercury as the glutathione conjugate

Gln and Gly are transported into the cell via the corresponding amino acid transporters

2015;8:Cd010497

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Besides upregulation of anti-oxidative stress capacity, another mechanism by which FoxO activation or low insulin drive may reduce oxidative stress includes the activation of Peroxisome Proliferator-activated receptor Gamma Coactivator 1 (PPGC-1), a nutrient sensing system that shifts substrate utilization towards fat and away from carbohydrate and increases mitochondrial biogenesis [66]