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Traditional big pharma is still rather cautious in trying new ways of getting things into the brain, although this is changing. Anthony King is a freelance science writer based in Dublin, Ireland References 1 H-L Liu et al, Proc

We next optimized a NRF2 transcriptional signature resulting in a set of 59 genes based on their contribution to the model and overlap with previously reported NRF2 signatures (Figs

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23 However, their use is limited by anticholinergic side effects, especially in elderly patients and those with cardiovascular disease