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The mRNA levels of GCLC and GS were both lower (50% and 30%, respectively) while mRNA levels of GCLM were unchanged

mtDNA mutations are implicated in various disorders, including mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS), maternally inherited Leigh syndrome (MILS), myoclonic epilepsy with ragged red fibers (MERRF), Lebers hereditary optic neuropathy (LHON), Kearns-Sayre syndrome, Pearson syndrome, and chronic progressive external ophthalmoplegia (CPEO)

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Lammi, Carmen, and Anna Arnoldi

Selected Data 1) This comprehensive study performed by the research team of McCoy et al aimed to develop metabolically stable AngIV analogs with enhanced blood-brain barrier (BBB) permeability and procognitive activity, specifically focusing on a molecule named Dihexa

MOTS-c vs NAD+: How Two Mitochondrial Compounds Compare and When a Clinic Uses Both MOTS-c and NAD+ both target mitochondrial function, but through different pathways