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La evidencia clnica es heterognea, pero el encuadre fisiopatolgico resulta coherente en subgrupos

Curcumin has been shown to change signaling pathways that control synaptic plasticity, raise the amount of neurotrophic factor from the brain (BDNF), a protein essential for neuron survival and mental performance, and reduce -amyloid accumulation

& Wanders, R.J.A

Hormonal replacementtherapy does not affect self-estimated pain or experimental pain responsesin post-menopausal women suffering from fibromyalgia: a double-blind,randomized, placebo-controlled trial

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