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A uniform 2,5-dihydroxybenzoic acid layer as a matrix for MALDI-FTICR MS-based lipidomics

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The most dramatic difference is observed when measuring protein levels between stage 1 and stage 3 konzo, where the most significant differences are observed with the lower limit of the 95% CI for unaffected siblings being 1.78 g/ml being as compared to the upper limit of 1.36 g/ml for the 95% CI for those with stage 3 (Supplementary Fig

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It has been demonstrated that all these pathological mechanisms triggered simultaneously by HI associated with IR produce, both directly and indirectly, through the triggering of arterial hypertension, an increase in LV mass, also due to an increase in intramyocardial and epicardial fat, with concentric LV remodeling, increased myocardial fibrosis, and diastolic dysfunction

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