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104 Some studies suggest that leptin receptors on Kupffer cells (KCs) and sinusoidal endothelial cells contribute to the expression of matrix-remodeling enzymes, thereby initiating fibrosis through hepatic stellate cells (HSCs) activation

I had all these problems before starting methyl-B12 so they weren't new, but they got many times worse than usual once I started the B12

The administration of monoclonal antibodies against Nogo-A had favorable results in the experimental scenario, as it rescued myelination and induced axonal repair in EAE rats (58)

Probably such antioxidant activities are at the core of its biological benefits

BIOCHEMISTRY OF VITAMIN B12 2.1

doi: 10.1002/adfm.201802227 133