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doi:10.1007/s11130-019-00771-5

Currently, however, there is a severe lack of human clinical data to support these claims, and fewer than five human trials are indexed in major databases, most with small sample sizes or unclear methodologies

In models of HFD feeding, diabetes, and insulin resistance, AX supplementation attenuates neuroinflammation, oxidative stress, and cognitive impairment, while modulating nutrient-sensing, inflammatory, and neuronal survival pathways [88,89,90,91]

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[DOI] [PubMed] [Google Scholar] [154].Tanaka T, Naganuma A, Imura N, Toxicology 60 (1990) 187198