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It can pass easily to the brain and is both water and fat-soluble Liu and colleagues tested aged rats with oral acetyl-L-carnitine and lipoic acid to see if the supplementation reduced mitochondrial aging in the brain [1] A group from Oregon State University reviewed the literature and suggested that together, acetyl-L-carnitine and lipoic acid were able to protect the heart from aging as well as reverse age-related changes [2]
SHMT2 reduces fatty liver but is necessary for liver inflammation and fibrosis in mice
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Budama-Kilinc Y, Cakir-Koc R, Kecel-Gunduz S, Kokcu Y, Bicak B, Mutlu H, et al
M., Yang, Z
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