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Deficiency makes you highly susceptible to bone fractures

10.1016/j.jalz.2018.06.3040 Alzheimers Dement 169 Moreno-LoshuertosR.Acin-PerezR.Fernandez-SilvaP.MovillaN.Perez-MartosA.de CordobaS
There have been numerous BOLD imaging studies in rats following changes in brain activity with amphetamine or methylphenidate (Ritalin) challenge (Preece et al., 2007

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Without adequate glutathione reserves, acetaldehyde accumulates in hepatocytes and crosses the blood-brain barrier, where it disrupts neurotransmitter synthesis and causes the cognitive symptoms of hangover
