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This was to see how GcvA initiates transcription of the glycine biosensor by binding to the gcvBp promoter, how GcvR inhibits GcvA binding to the promoter and how glycine stops GcvR binding to GcvA

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More research combining host metabolites and microbiota is needed to fully understand these relationships

Farese AM, Cohen MV, Stead RB, Jackson W, 3rd, Macvittie TJ

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doi: 10.1038/s41419-024-06945-7 111 KasikovaLRakovaJHenslerMLanickovaTTomankovaJPasulkaJet al