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Generally well-tolerated: Clinical trials report good safety profiles with parenteral L-Carnitine, even at high doses (up to 50 mg/kg IV daily) [5] [8]

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Consistently, oral administration of a CutC/D inhibitor markedly reduced plasma TMAO levels and rescued diet-induced platelet hyperreactivity and thrombosis without significant toxicity or increased bleeding risk (Roberts et al., 2018)
