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Warkentin, T

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Complex III transfers electrons from coenzyme Q to cytochrome c with additional proton pumping, Complex IV reduces oxygen to water, generating a proton gradient, and Complex V utilizes this gradient to synthesize ATP from ADP and inorganic phosphate

Therefore, we speculate that glial cell interaction may be the key mechanism of ferroptosis in Parkinsons disease (Figure 1)

Ligandin Retains and Albumin Loses Bilirubin Binding Capacity in Liver Cytosol
Signaling impairments within the glutamatergic and cholinergic systems are the main targets of currently approved AD therapies (Parsons et al., 2013)
