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This unique sex difference was subsequently confirmed in two follow-up studies, though with more modest reported improvements in female lifespan 7,8 , while a life shortening effect was observed in males 8

Zinc deficiency has been associated with an increased risk for several cancers [such as endometrial (369, 370), prostate (367, 368), pancreatic (368), breast (368), gynecological (371) and lung cancer (372)]
If that happens to be true it is possible testing for that enzyme could be preventive medicine

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Common effects include edema, tachycardia, and palpitations, and some patients experienced sudden death after taking this medication

Chen X, Li J, Kang R, Klionsky DJ, Tang D
