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In order for class III peroxidases to produce ROS, two conditions must be satisfied: 1) ion fluxes that lead to extracellular alkalization and 2) an abundant and recyclable oxidant as electron acceptor 37
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It has been demonstrated that abluminal membranes had both Na + -dependent taurine transport as well as facilitative transport while luminal membranes only had facilitative transport (Rasgado-Flores et al., 2012)

Buccafusco et al., 1995

2024 Jul 13];1403(1):38-47

A critical direction for future investigation involves defining the metabolic, immunological, and genetic determinants of treatment responsiveness
