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Moreover, Ras induces Ras-related C3 botulinum toxin substrate 1 (Rac1), which in turn leads to further stimulation of p38 MAPK and JNK (Trusolino et al., 2010)

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Quantitative Real-Time Polymerase Chain Reaction (PCR) Quantitative real-time PCR reaction was performed using Rotor-Gene Q real time PCR cycler (Qiagen, Germany)