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found that CDDO-Im treatment of high-fat diet-induced obesity in the wild-type mice can prevent lipid accumulation, but this phenomenon did not occur in Nrf2-knockout mice (Figure 4) (Shin et al., 2009)

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Oral administration of glutathione is not as effective at increasing glutathione levels in the body as injection or inhalation, but it is generally considered safe and may have some potential health benefits

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