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However, the exact mechanism by which IGF-1 improves insulin signalling has not yet be explained (other than indirect actions through lipid clearance from the bloodstream by inhibiting GH (lipolysis on adipocytes) and FFA uptake by muscles

97 KilbourneM.KuehnR.TosunC.CaridiJ.KeledjianK.BochicchioG.et al (2009)

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Therefore, gD has been the predominant candidate for HSV therapeutic antibody 23