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Recently, the knockdown of ten DCC members could reduce the elevated fat mass to normal levels in rict-1 mutants, suggesting that the DCC acted downstream of TORC2/rict-1 to negatively regulate the metabolism [116]

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58.00 Melanotan-1 (MT-1, Afamelanotide) synthetic -MSH analogue studied in preclinical melanocortin receptor and pigmentation research