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Description
In animal experiments, increases in VEGF were observed at both 2 h and 1 month following TBI, indicating impaired vascularity in both the short and long term (120, 121)
Gastroenterology 119 (3), 419437
Sian J, et al
Also, knockdown of CD44 strongly prevented clonal formation and inhibited tumorigenicity in a xenograft model, concluding that CD44 had a potential to be a CSC marker for colorectal cancer (CRC)
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157 This releases cytochrome c and apoptogenic factors such as AIF, Smac/Diablo, and endonuclease G, initiating apoptosome formation and caspase (-9, -3, -6, and -7) activation
