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AZD6244 and doxorubicin induce growth suppression and apoptosis in mouse models of hepatocellular carcinoma

114116 Both can also generate oxidant stress and LPO, which can be inhibited by lipophilic antioxidants such as vitamin E

doi: 10.1113/JP285793 64 Rodriguez ParisV.WongX

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A spectrum of hepatic pathologies, including fibrosis, non-alcoholic fatty liver disease (NAFLD), and hepatocellular carcinoma (HCC), often represent interconnected stages of progressive liver damage [2]
Aprs ajustements pour d'autres facteurs, le risque de maladie cardio-vasculaire tait significativement plus faible chez des sujets avec les niveaux de glutathion les plus levs par rapport aux sujets ayant les niveaux les plus faibles
