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About one third of diabetic patients suffer from painful neuropathy [13]

Probably, the best studied polyphenol is resveratrol, which is able to modulate lipid metabolism [225], but also to extend lifespan and reduce oxidative stress by affecting the unfolded protein response of the endoplasmic reticulum (UPR ER ), mimicking the response to calorie restriction [7]

Not for human use or diagnostic/therapeutic applications

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They sit in a specific regulatory category known as Research Use Only (RUO)
