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148,149 The Met-358 is at the P1 position, which is located in the reactive site, and determines anti-protease activity of AAT

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Cysteine but not glutathione modulates the radiosensitivity of human melanoma cells by affecting both survival and DNA damage

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Moreover, studies involving ApoJ gene knockout have shown reduced A fibril formation and prevention of A-induced neuronal death, suggesting that ApoJ might also contribute to AD pathology under certain conditions