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For example, studies in mice using gut microbial metabolites that restore intestinal barrier function and reduce inflammatory cytokines also resulted in lower BP [96]

2015;117(2) [Google Scholar] 186.Chen X., Qiu Y., Zhang J., Guo Y., Ding Y., Lyu F

DiNardo CD, Lachowiez CA, Takahashi K, Loghavi S, Xiao L, Kadia T, Daver N, Adeoti M, Short NJ, Sasaki K, Wang S, Borthakur G , Issa G, Maiti A, Alvarado Y, Pemmaraju N, Montalban Bravo G, Masarova L, Yilmaz M, Jain N, Andreeff M, Jabbour E, Garcia-Manero G, Kornblau S, Ravandi F, Konopleva MY, Kantarjian HM

Additionally, it is worth investigating whether GA involves other mechanisms in regulating blood pressure and the direct clinical evidence for GA treatment of arterial stiffness
[5] Note: this first reaction catalyzed by pyruvate dehydrogenase is the step at which the pyruvate dehydrogenase complex exerts its substrate specificity

AAV-AADC phase-I clinical trials demonstrated safety and a significant improvement of both motor and non-motor symptoms as assessed by the Unified Parkinson Disease Rating Scale (UPDRS), a decrease in OFF-time duration without an increased effect of ON-time dyskinesias, as well as an increase in the uptake of the AADC tracer at PET, which was used as a measure of gene expression (Christine et al