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doi:10.1186/1471-244x-14-s1-s1 Aggarwal R, Kunik M, Asghar-Ali A

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In the oral cavity, LL-37 (a cathelicidin), histatins (salivary peptides), and human beta-defensins (HBDs) are produced continuously but their expression is suppressed by chronic inflammation, poor nutrition, and aging, contributing to periodontal disease progression