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457 In triple-negative breast cancer (TNBC), LPA-LPAR3 signaling activates TRPC3 channels, leading to increased intracellular calcium levels, activation of the transcription factor NFAT, and upregulation of IL-8, which collectively promote the expansion of ALDH CSC populations

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When levels dip too low, your body becomes more susceptible to inflammation and oxidative stress, which can worsen chronic pain and fatigue

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