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Interestingly, propionic acid, which is significantly elevated in propionic acidemia, can have direct effects on GI physiology
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"Nitric oxide as a cellular antioxidant: a little goes a long way." Free radical biology and medicine 40.3 (2006): 501-506
PMID 17641258
In aged astrocytes, lipolytic defects (e.g., reduced adipose-triglyceride lipase activity) exacerbate lipid droplet accumulation, converting protective storage into neurotoxic reservoirs
This opens avenues for exploring their potential as therapeutic agents in cancer treatment
