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A-kinase anchoring proteins (AKAPs) act as scaffolds for localizing protein kinases and phosphatases to specific sub-cellular domains connecting them with their substrates, which include GPCRs, ion channels and neurotransmitters [6264]
Proc Natl Acad Sci USA 95:1573015734 Betz H, Harvey RJ, Schloss P (2001) Structures, diversity and pharmacology of glycine receptors and transporters
Use at least four sites and cycle through them systematically
