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Inevitably, even minor alterations in FcRn binding properties of a protein fusion can therefore affect the ability of the receptor to rescue it from intracellular lysosomal degradation

However, astrocytes are more resilient to rotenone treatment than neurons, being its mitochondrial dysfunction tightly associated with increased neuronal death [2-4,74]

Activated intestinal macrophages in patients with cirrhosis release NO and IL-6 that may disrupt intestinal barrier function

Table 1 summarizes data from preclinical studies

& Beyersmann, D
, Guo, Z
