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In addition, Treg cells likely control atherosclerotic lesion inflammation resolution as recent studies demonstrated that Treg cells regulate efferocytosis in atherosclerotic lesions by secreting IL-13 to stimulate macrophage production of IL-10 to induce Vav-1 activation of Rac1 and increased efferocytosis (215)

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In a transgenic prostate adenocarcinoma mouse model, BITC limited the progress of prostatic intraepithelial neoplasia (PIN) to a well-differentiated carcinoma (31)

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10.1039/c3mt20231c [DOI] [PubMed] [Google Scholar] Durnam DM, & Palmiter RD (1981)

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