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Blood 108(11):2123, 2006

The mixture was vortexed and centrifuged (5 min, 16,000 g) several times during 1 h

Furthermore, A is able to promote the hyperphosphorlyation of Tau in both the cytosolic and synaptic compartments, which has been suggested as a potential explanation of the prion-like seeding hypothesis of Tau transmission inter-neuronally, accounting for the phosphorylated Tau detected in the CSF of AD patients (Wu et al., 2018

c-MET signaling pathway [1] Beyond the classical HGF-dependent activation pathway, c-MET can also be activated through non-canonical pathways via interactions with other receptors such as integrin 64, EGFR, CD44v6, Plexin B, HER2, HER3, and AXL
10.1038/nm.2538 165 WeilandA.WangY.WuW.LanX.HanX.LiQ.et al (2019)
