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Circulation 109: 544549
25-28, 1995, published in SPIE Vol

While polyrotaxanes have been extensively studied and have shown promise, our perspective is that simpler CD-based rotaxanes, particularly [2]-rotaxanes, hold even greater potential for clinical applications
doi:10.1111/j.1600-0773.1948.tb03352.x
This immune-modulating effect may support calmer, more resilient skin

Using advanced tracer methodologies, the researchers identified a fascinating metabolic phenomenon they termed "brain glucose steal." Due to systemic mitochondrial impairment, non-brain organs were essentially stealing glucose intended for the central nervous system, starving the brain of energy and driving cognitive dysfunction