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In ApoE / mice subjected to chronic mild stress, lipid metabolism disorders, increased adipocyte hypertrophy, and reduced PPARG gene expression promote AS, while PPARG exhibits an anti-ferroptosis effect (Mao et al., 2023)

In human CECs (HCECs) exposed to phenylarsine oxide (PAO), a highly toxic trivalent arsenical, significant oxidative stress was reported by Kandhari et al., accompanied by ferroptotic cell death (115)

These tests are Standardised Mini-Mental State Examination (SMMSE), 26 attention and processing speed (Trail Making Test-A [TMT-A], executive functions (TMT-B and Stroop Color Word Test), 59 working memory (Digit Span subtest from Wechsler Adult Intelligence Scale-IV [WAIS-IV]) 60 and spatial span subtest Wechsler Memory Scale-III [WMS-III]), 28 visuo-spatial functions (Clock Drawing Test, CDT)

Wu, G., Knabe, D

695 On the contrary, GPX4 expression in neurons was downregulated at 4 weeks after spinal cord compression and upregulated at 8 weeks, 695 suggesting that it may promote functional recovery after chronic compression SCI

The mechanism of GSH-mediated biofilm disruption is possibly due to a concentration-dependent increase in GSH acidity that triggers cleaving of the matrix components