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In various PD models, including toxin-induced and inherited forms in mice, rats, fruit flies, and induced pluripotent stem cells, TZ increases brain ATP levels, slowing or preventing neuronal loss

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[DOI] [PMC free article] [PubMed] [Google Scholar] 30.Cappadoro M, Giribaldi G, OBrien E, Turrini F, Mannu F, Ulliers D, Simula G, Luzzatto L, Arese P

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Conversely changes in L-carnitine gut metabolism could also reflect alterations in its endogenous use as part of the L-carnitine system