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Kurarinone regulates Th17/Treg balance and ameliorates autoimmune uveitis via Rac1 inhibition
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Several compensatory mechanisms can counteract these therapeutic interventions, allowing tumor cells to evade their effects
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Disregulation of nutrient sensing 6
In mouse models of ASCVD (e.g., LDLR -/- ), a high-fat diet expands bone marrow progenitors and promotes myelopoiesis, accompanied by long-term epigenetic changes linked to NLRP3 inflammasome activation and increased IL-1 secretion
