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Patients on long-term metformin therapy should be monitored for vitamin B12 deficiency and may require supplementation

The human brain is extraordinarily good at identifying a narrative

In the blood, about 80% of cobalamin is bound to haptocorrin, forming holohaptocorrin, a complex that has a dual function: (1) holohaptocorrin conveys cobalamin to the liver, where it taken up through endocytosis (mediated by asialoglycoprotein receptor, ASGPR)

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In synthesizing TB-500, researchers aimed to mimic these regenerative effects to offer therapeutic support for physical recovery

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