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The role of hca2 (Gpr109a) in regulating macrophage function

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doi: 10.3390/cancers12041045 27 Rubbert-RothAEnejosaJPanganALHaraouiBRischmuellerMKhanNet al

On the other hand, VEGF-mediated cell invasion is promoted by the expression of MT (membrane type)-MMP (matrix metalloproteinase), MMP-2, MMP-9 and urokinase plasminogen activator which degrade the basal membrane and extracellular matrix allowing migration of endothelial cells and the formation of capillary sprouts [123, 125]