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Compound K Compound K is a ginsenosides-derived bioactive metabolite, which is formed through the metabolic process of ginsenosides by gut microbiota or by enzymatic conversion during the steaming and drying of Radix Ginseng [188]

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Another FXR antagonist, caffeic acid phenethyl ester, reduces ceramide synthesis, mitochondrial acetyl coenzyme A levels, pyruvate carboxylase activity, and hepatic glucose production