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Specifically, heightened TMAO levels have been linked to a heightened risk of cardiovascular events, including myocardial infarctions and cerebrovascular accidents ( Moreover, studies have demonstrated that TMAO plays a role in promoting inflammatory responses and oxidative stress in the body, which are critical factors in the advancement of kidney disease

Arch Biochem Biophys 80:333336

152,156,159162 Natural compounds Many natural compounds, including CPMs, are considered promising in the treatment of MASLD
In mice, FATP5 ( SLC27A5 gene) is involved in body weight regulation, while in humans SLC27A5 expression is increased in patients with early-stage non-alcoholic fatty liver disease [20, 21, 35]

2023, www.mayoclinic.org/drugs-supplements-l-arginine/art-20364681#:~:text=L%2Darginine%20isnt%20recommended,if%20you%20have%20these%20conditions

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