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We also discuss immunotherapy, including how engineered T-cells can be used to defeat childhood and adult cancers
[DOI] [PubMed] [Google Scholar] 592.Coelho, T

Sun exposure is the largest environmental accelerant of skin aging, primarily through UV-driven DNA damage in keratinocytes and free radical generation that degrades collagen

By contrast, several mutations that decrease the tone of the GH/IGF-1 axis are associated with extended longevity in mice

Intlekofer AM, Dematteo RG, Venneti S, Finley LW, Lu C, Judkins AR, Rustenburg AS, Grinaway PB, Chodera JD, Cross JR, and Thompson CB

[DOI] [PMC free article] [PubMed] [Google Scholar] 46.Belsky D.W., Caspi A., Corcoran D.L., Sugden K., Poulton R., Arseneault L., Baccarelli A., Chamarti K., Gao X., Hannon E., et al
