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Oxidized Linoleic acid metabolites regulate neuronal morphogenesis in vitro

Mitochondrial dysfunction in autistic patients with 15q inverted duplication

While the canonical signalling pathway engaged upon MCR activation is the increase in cyclic-AMP, it was found that inhibition of human lung fibroblast proliferation and differentiation by Gs-coupled receptors is not predicted by the magnitude of cAMP response (176), suggesting that the involvement of other pathways should be investigated to understand these actions

N Engl J Med 318 (18): 1159-62, 1988

This may not seem like a huge difference, but in the world of peptides, even a single amino acid added or subtracted can lead to huge changes

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