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( b ) The expression of cytosolic or nuclear IDO1 in U2OS cells treated with 100 M H 2 O 2 or combined with pre-treated with 5 mM NAC for 12 h was analyzed by Western blot

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PPAR is a member of PPARs, a group of nuclear hormone transcription factors whose presence at key sites involved in pain procession, such as the spinal cord, has been demonstrated as the primary modulator, increasing the expression of anti-inflammatory cytokines (IL-10) and reducing pro-inflammatory cytokines [122]

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