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The colloids revealed moderate PAS reactions, while the reactions were absent in the vacuoles of colloids

doi: 10.1146/annurev-med-070909-182917 115 RoopRPMaCX

Impacts, causes and biofortification strategy of rice selenium deficiency based on publication collection

Emerging translational strategies These include SGLT2 inhibitors, PARP inhibitors, necroptosis blockers [216], ferroptosis inhibitors [153], and NLRP3-targeting compounds [59, 60, 145], which have demonstrated significant efficacy in experimental models and, in selected settings, preliminary benefits in clinical studies [153, 216]

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However, despite their health benefits, the low absorption rate of polyphenols (approximately 510% via the small intestine) and their rapid metabolism and excretion significantly limit their ability to reach target tissues (114)