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In a rodent model subjected to chronic alcohol exposure, NAC was found to upregulate Nrf2, resulting in a decrease in hippocampal oxidative stress, as evidenced by a lower GSSG/GSH ratio [44]

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Redox regulation of UPR members The ER has an oxidative environment favoring the folding proteins, through the formation of disulfide bridges, which contributes to the redox state generating H 2 O 2 as a constitutive ROS production (Casas-Martinez et al

Shivaprasad DP, Taneja NK, Lakra A, Sachdev D

In cancer cells, mutations in succinate dehydrogenase subunit B (SDHB) cause susceptibility to familial pheochromocytoma 99 and familial paraganglioma 100 as well as gastrointestinal stromal tumors 101

In this context, redox copper has been the subject of extensive research and is recognized for its critical functions within the central nervous system