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Description
Often there are associations and correlations found but its rare and extremely exciting to find something that actual a direct effect

It has been widely reported that in different models of neurodegeneration, hesperetin can exert neuroprotective effects by counteracting free radicals generated during cellular metabolism and by enhancing endogenous antioxidant defence mechanisms 220 , 221
Osawa H, Kita H, Ohnishi H, Nakazato M, Date Y, Bowlus CL, et al

Anything beyond that needs stronger evidence

Activation of arcuate nucleus glucagon-like peptide-1 receptor-expressing neurons suppresses food intake

In the two crystal structures of normal human G6P, Pro172 is seen exclusively in the cis conformation, while in the crystal structure of one disease causing mutant (variant Canton R459L), Pro172 is seen almost exclusively in the trans conformation
