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Elevated circulating IGF-1 led to an activation of the IGF-1PI3KAkt signalling pathway, causing augmented mTOR phosphorylation and higher phospho-FoxO/total FoxO ratio in skeletal muscle of LC supplemented rats [33]

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Bone Health In a mouse model of osteoporosis, L-carnitine and isovaleryl-L-carnitine stimulated bone formation, improving bone turnover, bone density, bone size, and bone structure [55]

Age-Related Decline L-carnitine levels naturally decline with age, leading to reduced muscle mass, increased fat accumulation, and impaired mitochondrial function