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Complement deficiency affects the clearance of compounds, leading to elevation in autoantigens and causing SLE

10.1007/s00280-014-2503-z 145 TsumuraA.HayakawaT.KumakiY.TakebayashiS.SakaueM.MatsuokaC.et al (2006)

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687 This was demonstrated for the design of protein-sensing riboswitches in CFE systems

This revision came after reports of local IGF-1 production in non-hepatic tissues, including bone [142], demonstrating that IGF-1 acts as both an endocrine and autocrine/paracrine growth regulator

Since tumor cells with certain oncogenic mutations are very sensitive to ferroptosis, triggering ferroptosis may also have significant therapeutic potential for ferroptosis-sensitive tumor cells (Chen P.-H