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The protective efficacy of NAC and other potential pulmonary therapeutics (surfactant, liquivent, dexamethasone, and anti-sense syk oligonucleotides) was evaluated in a nerve agent-exposed animal model (Nambiar et al., 2007)

Using a typical estimate of volume of distribution for phenytoin of 0.7L/kg (Table 1), the loading dose can be calculated as follows: This relationship can also be used to calculate top-up doses that may be required if the drug is already present but the concentration is too low

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PDE5 inhibitors can cause major side effects, so researchers are investigating natural bioactive compounds that can alleviate and cure ED [57]

Das KC, Muniyappa H
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