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Int J Radiat Oncol Biol Phys 96(2S):E335-E336, 2016

While this idea is somewhat simplified, its intriguing His hypothesis suggests that the sudden influx of B12 can kickstart repair processes, and if there has been long-standing damage, the rapid onset of these processes might overwhelm the system, causing a temporary worsening of symptoms

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In summary, NaBPC157 could interfere with the NO-effects in both gastric mucosal integrity and blood pressure maintenance in a particular way, especially when combined with L-arginine, having a more prominent and/or particularly different effect on NO