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The expression of adhesion molecules on endothelial cell surfaces induced by TNF- has also been shown to be inhibited by sulforaphane via the inhibition of the activation of p38 MAPK (not JNK), and, interestingly, this effect is not mediated via Nrf2 expression [129]

Infectious etiologies of parkinsonism: pathomechanisms and clinical implications

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10.3892/ijmm.2021.5029 [DOI] [PMC free article] [PubMed] [Google Scholar] Jomova K., Valko M

Their structure includes multiple hydroxyl groups that facilitate the neutralization of free radicals, decrease oxidative stress, and modulate nitric oxide bioavailability, potentially enhancing endothelial function and metabolic health [340]