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In addition, it is one of a few antihyperglycemic agents associated with improvements in cardiovascular morbidity and mortality, which is a major cause of death in patients with type 2 diabetes

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Even if crystals form, internal motions within the protein can lead to averaged electron density maps, blurring out the finer details and limiting the resolution of the determined structure (Hekstra, 2023)

Pandey K.B., Rizvi SI

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